Nephrotic Syndrome Complications

Nephrotic syndrome is a kidney disease with a group of symptoms and complications. How can patients know they are patients with Nephrotic Syndrome, here are some complications that they can refer to.

　　Dehydration

　　Low protein levels may lead to a reduction in blood volume. In severe cases, intravenous fluids may be given to boost the body’s water content.

　　Blood clots

　　Proteinuria should be responsible for this complication for protein has the ability to prevent clotting in the blood. Protein in urine is an outstanding symptom of nephrotic syndrome. Blood clots may increase the risk of shock, myocardial infarction and pulmonary embolism etc.

　　High blood cholesterol and elevated blood triglycerides

　　When the level of the protein albumin in your blood falls, your liver makes more albumin. At the same time, your liver releases more cholesterol and triglycerides.

　　Osteomalacia and osteitis fibrosis cystica

　　With nephrotic syndrome developing, the vitamin D-binding protein and its complexes leak into urine increase the risk of those complications through a combination of calcium absorption and secondary hyperparathyroidism.

　　Poor nutrition

　　Loss of too much blood protein can result in malnutrition. This can lead to weight loss, but it may be masked by swelling.

　　High blood pressure

　　Damage to your glomeruli and the resulting buildup of wastes in your bloodstream (uremia) can raise your blood pressure.

　　Acute kidney failure

　　If your kidneys lose their ability to filter blood due to damage to the glomeruli, waste products may build up quickly in your blood. If this happens, you may need emergency dialysis — an artificial means of removing extra fluids and waste from your blood — typically with an artificial kidney machine (dialyzer).

　　Chronic kidney failure

　　Nephrotic syndrome may cause your kidneys to gradually lose their function over time. If kidney function falls low enough, you may require dialysis or a kidney transplant.

　　Infections

　　A large quantity of immunoglobulin loses in urine when Nephrotic Syndrome occurs. Plasma proteins are also affected accordingly. It turns out that the formation of antibody becomes a big problem, which contributes to low immunity. To make things worse, the application of steroids and cytotoxic drugs is no good to immune system.